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Allergan and Editas Medicine Strike R&D Alliance for Eye Diseases
March 14, 2017
Allergan plc and Editas Medicine Inc., a genome editing company, announced that Allergan’s subsidiary, Allergan Pharmaceuticals International Limited, and Editas Medicine have entered into a strategic research and development agreement. The agreement states that Allergan will have full access and licensing options for up to five of Editas's genome-editing ocular programs. The deal covers programs that target serious diseases based on Editas's CRISPR genome editing platform, including CRISPR/Cas9 and CRISPR/Cpf1.
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a programmable tool that targets specific areas of genetic code and edits DNA at specific locations in the human genome. This allows researchers to modify genes and potentially create medicines with sustainable treatment effects.
Also included in the agreement is Editas's lead program, which is currently preclinical, for the potential treatment of LCA10 (Leber congenital amaurosis)-a rare, inherited retinal degenerative disease that appears in childhood and leads to blindness.
Key Findings of the NIAGARA and HIMALAYA Trials
November 8th 2024In this episode of the Pharmaceutical Executive podcast, Shubh Goel, head of immuno-oncology, gastrointestinal tumors, US oncology business unit, AstraZeneca, discusses the findings of the NIAGARA trial in bladder cancer and the significance of the five-year overall survival data from the HIMALAYA trial, particularly the long-term efficacy of the STRIDE regimen for unresectable liver cancer.
ROI and Rare Disease: Retooling the ‘Gene’ Value Machine
November 14th 2024Framework proposes three strategies designed to address the unique challenges of personalized and genetic therapies for rare diseases—and increase the probability of economic success for a new wave of potential curative treatments for these conditions.
Cell and Gene Therapy Check-in 2024
January 18th 2024Fran Gregory, VP of Emerging Therapies, Cardinal Health discusses her career, how both CAR-T therapies and personalization have been gaining momentum and what kind of progress we expect to see from them, some of the biggest hurdles facing their section of the industry, the importance of patient advocacy and so much more.
