ProFuse Announces New Drug Development Platform for Muscle Loss Prevention Medication

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Weight loss is a serious issue amongst Americans. While obesity is the main condition related to this issue, weight loss is also a major concern for many patients. It’s not uncommon for people to lose weight either directly from being sick or as a side effect of medication.

Even for people looking to lose weight on purpose, a loss of muscle mass is still a major concern. While it’s generally healthy to reduce the amount of fat the body is carrying, maintaining muscle mass is always a positive.

The recent boom in GLP-1 medications has brought this issue to the spotlight. With patients successfully losing weight due to these medications, it’s more important than ever to find ways to get these people to maintain their muscle mass. Aside from people using GLP-1s, a loss of muscle mass is a significant concern for aging patients as well.

ProFuse Technology is a company focused on the development of muscle tissue in laboratory settings. The company recently announced a new drug discovery platform designed to specifically develop new treatments for the maintenance of muscle mass.

In a press release, ProFuse CEO and co-founder Guy Nevo-Michrowski said, “ProFuse's timing for entering the market is excellent. Weight-loss drugs lead to muscle mass loss, prompting pharmaceutical companies to invest significant resources in developing innovative treatments that combine GLP-1 weight-loss drugs with muscle mass preservation therapies. As a result, several major deals in the muscle preservation drug sector have been signed in recent years, with transaction values reaching several billion dollars. This trend signals a significant window of opportunity for new technologies in this field, including ours."

Alongside this announcement, ProFuse also revealed that Anat Naschitz would being joining its board of directors. In the same press release, Naschitz said, “I am grateful to ProFuse for the opportunity to be part of the journey in discovering and developing drugs that prevent muscle mass loss—an important clinical need requiring a solution. I was impressed by the company's and management's ability to demonstrate resilience in the face of challenges requiring adaptation and change. This adaptability was evident both at the industry level—strategically pivoting toward new directions—and at the operational level, where the company exhibited remarkable flexibility, strategic decision-making, and an unwavering positive spirit."

This is just the latest addition to ProFuse’s board. In April of 2024, the company announced that Professor Shulamit Levenberg of the Technion Faculty of Biomedical Engineering would be joining its scientific advisory board.²

In a press release issued at the time, ProFuse’s scientific founder and board member Professor Eldad Tzahor said, “Muscle associated diseases such as muscle wasting poses a growing health challenge, which is contributed by aging, chemotherapy and consumption of drugs for weight loss and diabetes. We are thrilled to welcome Professor Levenberg's to our Scientific Advisory Board, in order to bolster our pioneering innovative approaches towards muscle regeneration and maintenance."

In the same press release, Levenberg added, “I am excited to join ProFuse Technology's Scientific Advisory Board and contribute to advancing the technology of ProFuse towards therapeutic applications. This collaboration has the potential to significantly improve the lives of many patients suffering from muscle-related diseases."

Sources

1. Startup ProFuse Launches Pioneering Drug Discovery Platform for the Prevention of Muscle Loss. ProFuse Technology. April 3, 2025. https://www.prnewswire.com/news-releases/startup-profuse-launches-pioneering-drug-discovery-platform-for-the-prevention-of-muscle-loss-302419779.html
2. Muscle Cultuvation Startup Profuse-Technology Welcomes Renowned Technion Professor to its Scientific Advisory Board. ProFuse Technology. April 22, 2024. Accessed April 4, 2025. https://www.prnewswire.com/news-releases/muscle-cultivation-startup-profuse-technology-welcomes-renowned-technion-professor-to-its-scientific-advisory-board-302122768.html