Roche and AZ Bladder Cancer Treatments Set for Blockbuster Status

The urological cancers market, including bladder, kidney, prostate and testicular cancer, will increase from $17.9 billion in 2015 to $35.9 billion by 2022, according to GBI Research.

The company’s latest report states that this strong market growth will be driven by the predicted emergence of targeted therapies for bladder cancer and increasing prostate and kidney cancer prevalence.

GBI analyst Adam Bradbury commented: “It is predicted that two new urological cancer drugs for the treatment of bladder cancer – Roche’s atezolizumab and AstraZeneca’s durvalumab – will achieve blockbuster status by 2022. The former is anticipated to achieve revenue of $2.5 billion in 2022, following approval from late 2016, and its uptake will be driven by a lack of targeted therapies for bladder cancer, along with increasing prevalence and clinician familiarity. The latter is anticipated to generate $1.2 billion in 2022, following its expected approval in 2017."

Although drugs such as atezolizumab and durvalumab are not expected to surpass the revenues generated by the currently marketed drugs Opdivo or Xtandi due to a competitive market landscape, their approval and uptake will cause shifts in market dynamics.

Bradbury added: “Key players Johnson & Johnson and Pfizer, for example, are predicted to have decreasing market shares due to decreasing or static drug revenues as the overall market revenues rise. Those of Roche and Bristol-Myers Squibb (BMS), on the other hand, will increase due to the uptake of recently approved and upcoming immune checkpoint inhibitors such as atezolizumab, and BMS’s Opdivo and Yervoy. Astellas is forecast to maintain its strong market share through to 2022 due to increasing Xtandi revenues.”

Global Urological Cancer Market to 2022 - Strong Growth Driven by Rising Prevalence, Increased Uptake of Hormone Therapies and Approval of Novel Biologics